• Skip to primary navigation
  • Skip to main content
  • Skip to footer
Prior Scientific

Prior Scientific

Experts in Precision Positioning and Microscope Automation

  • Products
    • Automated Imaging Systems
      • OpenStand-U
      • OpenStand-M
      • OpenStand-L
      • OpenStand-V
    • Imaging Components
      • Motorized Stages
      • Focus Mechanisms
      • Laser Autofocus
      • Filter Wheels, Turrets & Shutters
      • Controllers & Joysticks
      • Robotic Sample Loaders
      • Physiology Platforms
      • Motorized Vertical Stages
    • Microscope Automation
      • Evident Olympus Microscope Automation
      • Nikon Microscope Automation
      • Leica Microscope Automation
      • Zeiss Microscope Automation
      • Automated Custom Imaging Systems
      • Other Microscope Brands
    • Nanopositioning Devices
    • Vibration Control
    • Custom Solutions & Contract Manufacturing
  • About
  • Applications
  • Blog
  • Contact Us
  • News
  • Technical Support
  • US Shop
  • United States
    • English
    • Deutsch
    • 日本語
    • 简体中文
  • Automated Imaging Systems
    • OpenStand-L
    • OpenStand-M
    • OpenStand-U
    • OpenStand-V
  • Imaging Components
    • Motorized Stages
    • Focus Mechanisms
    • Laser Autofocus
    • Filter Wheels, Turrets & Shutters
    • Controllers & Joysticks
    • Robotic Sample Loaders
    • Physiology Platforms
    • Motorized Vertical Stages
  • Microscope Automation
    • Evident Olympus Microscope Automation
    • Nikon Microscope Automation
    • Leica Microscope Automation
    • Zeiss Microscope Automation
    • Automated Custom Imaging Systems
    • Other Microscope Brands
  • Nanopositioning Devices
  • Vibration Control
  • Custom Solutions & Contract Manufacturing
Home » Blog » How to specify the correct nanopositioning system

How to specify the correct nanopositioning system

27.02.23

 

The 6 factors to consider for perfect nanopositioning

If you’ve not previously used a nanopositioning system, or had cause to specify one for a while, then it’s worth taking time to consider some of the key factors that will ensure a successful purchase. These factors apply to all applications in precision industrial manufacturing, science and research, photonics and satellite instrumentation.

1. Construction of nanopositioning devices

The science of nanopositioning, with exceptional resolution in the nanometer and sub-nanometer range, and response rates measured in sub-milliseconds, depends fundamentally on the stability, precision and repeatability of the mechanical and electronic technology used in each system. The first key factor to be considered when choosing a new system should therefore be the quality of its design and manufacture. Precision engineering and attention to detail will be obvious, being reflected in the methods of construction, materials used and the layout of component parts such as stages, sensors, cabling and flexures. These should be designed to create a robust and solid structure, which is free from flexing and distortion under pressure or during movement, interference from extraneous sources, or environmental effects such as thermal expansion and contraction. The system should also be constructed to meet the demands of each application; for example, the conditions under which a system used for the optical inspection of semiconductor wafers will have completely different operating criteria to one intended for use in areas of ultra-high vacuum or high radiation.

2. The motion profile

In addition to understanding the demands of the application, it’s also important to consider the motion profile that will be needed. This should take account of:

  • The required stroke length for each axis of motion
  • The number and combination of axes of motion: x, y and z, plus tip and tilt
  • The speed of travel
  • Dynamic motion: for example, the need to scan in both directions along each axis, the requirement for either constant or stepped motion, or the advantage of capturing images on the fly; i.e. while the attached instrument is in motion.

3. Frequency response

Frequency response is essentially an indication of the speed with which a device responds to an input signal at a given frequency. Piezo systems respond rapidly to command signals, with higher resonant frequencies producing faster response rates, greater stability and bandwidth. It should be recognized, however, that the resonant frequency for a nanopositioning device can be affected by the load applied, with an increase in load reducing the resonant frequency and thus the speed and accuracy of the nanopositioner.

4. Settling and rise time

Nanopositioning systems move extremely small distances, at high speeds. This means that settling time can be a crucial element. This is the length of time it takes for movement to decrease to an acceptable level before an image or measurement can subsequently be taken. By comparison, rise time is the elapsed interval for a nanopositioning stage to move between two command points; this is normally far quicker than the settling time and, most importantly, does not include the time required for the nanopositioning stage to settle. Both factors affect accuracy and repeatability and should be included in any system specification.

5. Digital control

Resolving the challenges of frequency response, together with settling and rise times, depends largely on the correct choice of system controller. Today, these are extremely advanced digital devices that integrate with precision capacitive sensing mechanisms to produce exceptional control at sub-micron positional accuracies and high velocities. As an example, our latest Queensgate closed-loop velocity controllers use digital notch filtering in conjunction with precision mechanical stage design. This approach ensures that resonant frequencies remain consistent even under significant changes of load, while providing fast rise times and short settling times – all of which are achieved with outstanding levels of repeatability and reliability.

6. Beware specmanship!

Finally, be aware that different manufacturers often choose to present system specifications in varying ways, which can make it difficult to compare like for like. Additionally, in some instances a system may perform well for particular criteria – usually those promoted by the supplier – but function poorly in other areas. If the latter are not crucial to your specific application, then this should not be an issue; it is, however, equally possible that if overlooked they may potentially have a detrimental impact on the quality of your later production or research activities. Our recommendation is always to talk to several suppliers to get a balanced view before deciding on the nanopositioning system that best meets your needs. As a leading manufacturer, which has been designing and manufacturing nanopositioning systems – including stages, piezo actuators, capacitive sensors and electronics – for over 40 years, we are always happy to provide advice and information on the different nanopositioning technologies and devices that are available.

Learn more

If you’d like to learn more, contact a member of our technical sales team.

 

More Blogs

Close up of a motorized xy stage on an OpenStand-V inverted imaging platform. imaging platform 27.07.26

Microscopy and Precision Positioning Glossary: Terms, Definitions and Industry Guide

Learn More
H100A compact precision motorized XY stage for upright microscopes 15.06.26

H100A Compact Motorized XY Microscope Stage for Precision Microscopy: Product Manager Q&A

Learn More
Three quarters view of the Prior motorized filter cube turret for multi-colour fluorescence imaging. 13.05.26

How a motorized filter cube turret expands microscope performance across advanced imaging workflows

Learn More
HF108B Filter Wheel: High‑Speed Fluorescence Imaging for Automated Microscopy Systems 21.04.26

HF108B Filter Wheel: High‑Speed Fluorescence Imaging for Automated Microscopy Systems

Learn More

Footer

Products

  • Automated Imaging Systems
  • Imaging Components
  • Microscope Automation
  • Nanopositioning Devices

Company

  • Custom Solutions & Contract Manufacturing
  • Applications
  • Technical Support
  • Careers

Resources

  • About
  • Blog
  • News
  • Contact Us

    Sign up to stay in the know...

    ✉

    Connect with us

    Prior Scientific Instruments Ltd.
    Units 3-4 Fielding Industrial Estate
    Wilbraham Road, Fulbourn
    Cambridge, CB21 5ET, UK

    inquiries@prior.com
    +44 (0)1223 881711

    Prior Scientific Inc.
    80 Reservoir Park Drive
    Rockland, MA. 02370
    U.S.A.

    info@prior.com
    +1 781 878 8442

    Prior Scientific Instruments GmbH
    Maria-Pawlowna-Str. 4
    07743 Jena
    Germany

    jena@prior.com
    +49 (0)3641 242 010

    Prior Scientific KK
    Kayabacho 3rd Nagaoka Bldg 10F,
    2-7-10, Nihonbashi Kayabacho
    Chuo-Ku, Tokyo 103-0025, Japan

    info-japan@prior.com
    +81 (0)3 5652 8831

    Prior Scientific Instruments (Suzhou) Ltd.
    Room 118, Meilihua Hemu Park,
    No. 393 Suhong Middle Road,
    Suzhou Industrial Park,
    Suzhou, 215000, China

    info-china@prior.com
    +86 (0)512 6617 5866

    Copyright © 2026 · Prior Scientific. Terms & Conditions | Privacy Policy | Impressum

    Manage Consent
    To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
    Functional Always active
    The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
    Preferences
    The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
    Statistics
    The technical storage or access that is used exclusively for statistical purposes. The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
    Marketing
    The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
    • Manage options
    • Manage services
    • Manage {vendor_count} vendors
    • Read more about these purposes
    View preferences
    • {title}
    • {title}
    • {title}